Well, basically yes. The way most pitched roofs are shaped is just like an aircraft wing or airfoil. The way it is the same as a wing is that in a storm the air will be rushing over the top of the roof and down the backside. This is the same for an airfoil, the air goes up over the top and down the back side causing areas of high pressure and low pressure. Where the airfoil is different than your roof is that on the airfoil the air passes beneath it whereas on your roof it does not, until of course there is structural failure of the roof
As you can see in the two illustrations, both the roof and the airfoil produce low pressure on top. In the illustration of the house you can see the high-pressure area on the side of the house. If one of the openings such as a door or window fail on the high-pressure side of the house the interior pressure of the home will increase. This will cause high pressure on the bottom of the roof to push up as well as the low pressure on the top pulling on the roof. Sometimes these combined forces will cause your roof to become airborne as it becomes detached from the house.
All of these forces working together at the same time tend to make the roof fail on the downwind or leeward side of the roof. That portion will become detached first and then the rest usually follows.
So there you go, it is a thing. Now I know you’ll be able to sleep at night and not let it keep you awake wondering about this question.
Take care out there,